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The weekend sees the initial Wear-Tyne derby since 2024, but will it be – Sunderland or Newcastle?
"Throughout the majority of last season, it was unthinkable Sunderland getting promoted and challenging with Eddie Howe's Newcastle, never mind being above them in the table," remarked football expert Chris Sutton.
"It is very different now, and the way they play makes me think they've got a real chance."
He is offering predictions for all 380 Premier League games this campaign, against artificial intelligence, readers and a variety of guests.
For week 16, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the eLions – the Football Association's recognised esports team – at the EA Sports FC European esports championship finals tournament, which is being held at Twickenham Stadium on Saturday.
Viewers can catch Uefa's video platform, Instagram Live and short-form video channels, as well as the official Twitch channel and YouTube and the national team's Twitch.
What are your thoughts with their forecasts? You can make your own predictions below.
The most commonly selected scoreline selected for each game is used in the leaderboards at the bottom of this page.
Predicting the right outcome (picking a win, draw or defeat) is worth 10 points. The exact score earns 40 points.
Ray, who competes for his club side and Manchester City as well as England, is entering the fray at the eEuros finals after passing the qualifying.
The final eight competitors will represent their nations at the finals in a single-elimination, competing for a substantial cash prize and a highly sought-after spot in the world finals play-offs, with Denmark's Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray remarked. "I have a really good coach by my side and preparation has been going well.
"It's always an honour to play for your country. Obviously when you are younger, you imagine doing it as an actual footballer, but when you pursue a career in this job and there is an chance to represent England, donning the national jersey is something unique.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him throughout the year just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"In my opinion he is the best player in the world so beating him in a tournament like this just delivers a massive injection of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The London club were outstanding against the Gunners at the end of November, when they secured a point after going down to 10 men, and it seemed here we go, they could potentially be challengers for the crown.
In the matches following, however, they were beaten physically by Leeds, looked uninspired against Bournemouth and this week got defeated by Atalanta in the Champions League.
So manager Enzo Maresca really needs a win here to get back on track, but it won't be easy because Everton are such a threatening team.
Their key midfielders are playing at the top of their game and Everton have got a bit of momentum at the moment.
Based on recent performances you would likely back Everton, while the most prudent prediction would likely be a draw, but I am not going to be sensible.
Chelsea haven't given me any good cause to back them recently, but I just have a hunch they will win this match because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be fascinating to see what we get from the Reds.
I was delighted for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday following all the controversy with Mohamed Salah this week.
Slot ought not to put up with that drama. I know Salah has been a legend for the club but at its core Slot just wants to win games and there is no ulterior motive in his team selection.
Liverpool changed their formation against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is selected for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's attention will be on winning this game, but it is a difficult fixture.
It's fair to say it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are defensively susceptible too.
Liverpool need to get back to a consistent run of form, but I am not sure how much their efforts at the San Siro will have drained them.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Wearside club have had the benefit of a free week while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Apart from their superb performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
The pattern suggests that trend to continue on Sunday, and their tiredness is likely to be a key element in how this game goes because of their rivals' high press.
Their match against Arsenal demonstrated how unwavering Regis le Bris's side are. They dominated the Gunners, and it was a joy to watch.
Everyone talks about how Granit Xhaka has been outstanding for the Black Cats, and he has been excellent, but Noah Sadiki, who plays in midfield with him, has also been one of the signings of the season and should be recognised too.
I am expecting this being the best game|most exciting fixture